Marilyn Vache, MD  
     
     

 

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Journal Articles

The Journal of Clinical Psychiatry, June, 2011: A reivew of twenty-five high-quality studies of homeopathy in psychiatric disorders concluded, “results do not preclude the possibility of some benefit.” I have no doubt about it. Davidson, et al., Duke University. Biological Psychiatry, May, 2011: In an experiment on rats, the equivalent of human dosing for five years with haloperidol (an old schizophrenia drug) and Zyprexa (a new one used for schizophrenia and mood disorders) confirmed prior suggestions that these drugs may cause loss of brain volume. Very sobering for all of us treating seriously ill patients. Vernon, et al. The Journal of Clinical Psychiatry, May, 2011. No surprises, just confirmation: Moderate exercise -- walking or jogging 4 miles an hour -- an average of 30 min per day doubled the remission rate for depression. The study was done at the Cooper Clinic in Dallas. Madhukar, et al. Long work hours can lead to sleep deprivation can lead to depression. Author: A Nakata. There seems to be a subset of chronic depression in late life associated with metabolic syndrome (overweight, large waist, high triglycerides, high blood pressure, and problems with blood sugar control). Do you think it’s reversible? I do! Vogelzangs, et al., Amsterdam. A big surprise here: Tardive Dyskinesia, a very difficult to treat complications of some psychiatric medications, responded well to an extract of 240 mg ginkgo biloba daily, an herb used in my practice for sexual dysfunction resulting from SSRI’s and more widely known for its possible use for memory loss. Zhang, et al., Beijing. Neurology, April 19, 2011 Huperzine, a traditional Chinese herb and now often found in supplements for memory loss, showed high doses (400 mg twice a day) gave cognitive improvement to patients with mild to moderate dementia. Results are for tests after 16 weeks. Rafii, et al.